A focus of the Centre is to explore the application of stem cell technologies for interventions in the ageing process to replace damaged cells and enhance tissue rejuvenation. The Centre has set up an induced pluripotent stem cell (iPSC) platform headed by Dr Zeng Xianmin from XCell/NxCell company that specialises in current technologies in stem cell and regenerative medicine. In addition, our Centre also has a platform for embryonic stem cells (ESCs) and neural stem cells (NSCs) derivation of motor neurons by Dr John Chua Jia En.
We are open to collaborative investigations from interested researchers. Please contact the centre for more information.
To stimulate animal studies in the biology of ageing, the Centre has a platform set up to facilitate health-span and life-span studies in mice amongst the local research community. The research directions will be principal investigator - initiated.
This platform could be used for testing of interventions designed to slow ageing, acquisition of longitudinal or cross-sectional data on specific aspects of ageing and other investigator- designed studies. In-house researchers will aid in frailty index scoring as well as other parameters relevant to ageing biology.
We are open to collaborations from interested investigators. Please contact the centre for more information.
Our Centre has a translational science platform set up to facilitate the understanding of how ethnicity, and lifestyles affect biological ageing in adults.
This platform could be used for functional testing such as aerobic fitness, walking speed, muscle and flexibility testing as well as arterial stiffness. Epigenetic parameters of ageing could also be measured to compare biological age in participants.
We are open to interested individuals or collaborations from interested investigators. Please contact the centre for more information.