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Centre for Healthy Longevity

About Us

About Us


Singapore has one of the best healthcare systems in the world and thanks to this, we are living much longer lives. In Singapore, women and men can expect to live up to age 86.1 years and 85.1 years respectively. However, this coupled with a lower fertility rate, Singapore is experiencing a drastic demographic shift that sees its population transition from an ageing to an aged one. As ageing is the most common and biggest risk factor for most chronic diseases, will likely see an increase in the prevalence of age-related disease and the healthcare costs that comes with it. This poses potential economic issues due to the decline in the proportion of working-age people that must meet the demand for increased costs of elderly healthcare.

The Centre for Healthy Longevity endeavours to delay ageing and increase the human healthspan, and research undertaken by the centre will transform the way we age and secure a healthier future for our people.

  • ​Be a global leader in ageing research and translation
  • Achieve major breakthroughs in extending human healthspan and lifespan

It's the Centre's mission to delay ageing, increase human healthspan, and maintain functionality and resilience. This is accomplished using a two-pronged approach where leading scientists conduct fundamental research which delineates the mechanistic pathways of ageing and is translated to human clinical studies to promote healthy longevity throughout the life course.

Faculty members

  • Prof Brian Kennedy—Director (Distinguished Professor, Department of Biochemistry and Physiology, Yong Loo Lin School of Medicine, NUS)
  • Prof Andrea Maier—Oon Chiew Seng Professor in Medicine, Healthy Ageing and Dementia Research, Department of Medicine, NUS
  • Dr Vincenzo Sorrentino—Assistant Professor

Clinical Faculty and Affiliates 

  • Angelique Chen—Executive Director & Associate Professor (CARE, DUKE- NUS)
  • Christopher Chen—Director (Memory Ageing and Cognition Centre, NUHS)
  • Matthew Chen—Associate Consultant (Department of Geriatric Medicine, NUH)
  • Huang Zhongwei—Associate Consultant (Clinician-scientist, Obstetrics & Gynaecology, NUH)
  • Koh Woon Puay—Director (Clinician Scientist Development Unit, NUS)
  • Melvin Leow—Senior Consultant (Department of Endocrinology, TTSH)
  • Will Loh—Research Director & Senior Consultant (Department of Anesthesiology, NUS)
  • Reshma Merchant—Head & Senior Consultant (Division of Geriatric Medicine, NUH)
  • Amartya Mukhopadhyay—Research Director (Alexandra Hospital); Assistant Professor (Division of Respiratory & Critical Care, NUH)
  • Mark Richards – Director (Cardiovascular Research Institute, NUS)
  • Raymond Seet—Co-Director of NUSMed Ageing Programme; Associate Professor (Division of Neurology, NUH)
  • Santhosh Seetharaman—Director (Healthy Ageing, Alexandra Hospital); Consultant (Division of Geriatric Medicine, NUH)
  • Ti Lian Kah—Academic Head & Senior Consultant (Department of Anesthesiology, NUS)
  • Laureen Wang Yi-Ting—Head (Well Programme, Alexandra Hospital); Consultant (National University Heart Centre, Singapore); Clinical Assistant Professor (NUS)

Visiting scientists

  • Prof Jing-Dong Jackie Han

Associates of CHL


  • Nanyang Technological University (A/Prof Fabian Lim – Exercise Metabolism and Physiology Lab)
  • Albert Einstein College of Medicine, New York, USA (Prof Nir Barzilai – Institute for Aging Research)

Public/ Private

  • GERO
  • PDL Health
  • SGInnovate
  • Bespoke Fitness
  • ActiveSG
  • SportMaster
  • Health Promotion Board (HPB)
  • Genome Institute of Singapore (GIS)